15th European Conference on Artificial Intelligence
|July 21-26 2002 Lyon France|
Hidde de Jong, Jean-Luc GouzÚ, CÚline Hernandez, Michel Page, Tewfik Sari, Hans Geiselmann
Methods developed for the qualitative simulation of dynamical systems have turned out to be powerful tools for studying genetic regulatory networks. We present a generalization of a simulation method based on piecewise-linear differential equation models that is able to deal with discontinuities. The method is sound and has been implemented in a computer tool called GNA.
Keywords: Qualitative Reasoning, Bioinformatics, model-based reasoning
Citation: Hidde de Jong, Jean-Luc GouzÚ, CÚline Hernandez, Michel Page, Tewfik Sari, Hans Geiselmann: Dealing with Discontinuities in the Qualitative Simulation of Genetic Regulatory Networks. In F. van Harmelen (ed.): ECAI2002, Proceedings of the 15th European Conference on Artificial Intelligence, IOS Press, Amsterdam, 2002, pp.412-416.